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KMID : 1035220210130020055
Korean Journal of Neuromuscular Disorders
2021 Volume.13 No. 2 p.55 ~ p.58
A Case of Glycogen Storage Disease Type V with Rhabdomyolysis after COVID-19 Vaccination
Kim Ho-Kyu

Kim Ye-Eun
Lee Hye-Lim
Abstract
Glycogen storage disease (GSD) type V, also known as McArdle¡¯s disease, is an autosomal recessive genetic disease caused by a mutation of the PYGM gene related to the synthesis of the myophosphorylase enzyme. Here, we presented the case of an 83-year-old woman who was admitted for progressively worsening weakness of her legs due to rhabdomyolysis after a COVID-19 vaccination. In the muscle biopsy, myopathy with subsarcolemmal glycogen accumulation was revealed and she was diagnosed with a mild form of GSD type V. Although COVID-19 vaccines are generally safe and encouraged for everyone, adverse events following COVID-19 vaccinations are increasing. We should pay attention to the side effects of COVID-19 vaccination including rhabdomyolysis.
KEYWORD
Glycogen storage disease type V, Rhabdomyolysis, COVID-19 vaccine
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